Biomarkers in Toxicology

Biomarkers in neurodevelopmental toxicology.

Biomarkers in environmental toxicology: state of the art.

Together with many other research-based disciplines, environmental toxicology has profoundly benefited from recent advances in molecular biology and analytical chemistry. As a result of these accomplishments, clinical and experimental studies of biomarkers have developed into a multidisciplinary research area. The IFCC has convened two conferences: to review biomarkers of chemical exposure, in ...

The role of biomarkers in reproductive and developmental toxicology.

A massive outbreak of methylmercury poisoning took place in the winter of 1971-1972 due to the consumption of homemade bread contaminated with a methylmercury fungicide. The longitudinal analysis of the mother's head hair, collected after delivery of the baby, provided a means of recapitulating exposure to methylmercury during pregnancy. Methylmercury is incorporated into newly formed hair at a...

Biomarkers in toxicology and risk assessment: informing critical dose-response relationships.

Tremendous advances have been made in the study of biomarkers related to carcinogenesis during the past 20 years. This perspective will briefly review improvements in methodology and instrumentation that have increased our abilities to measure the formation, repair, and consequences of DNA adducts. These biomarkers of exposure, along with surrogates such as protein adducts, have greatly improve...

Empowerment of Medical Toxicology in South Korea

In a recent issue of the Asia Pacific Journal of Medical Toxicology (APJMT), the importance of empowering medical toxicology in the Asia Pacific Region has been discussed. In the editorial by Dr. Afshari, it has been stated that national societies of medical toxicology are important infrastructure for the development of medical toxicology, and the Asia Pacific Association of Medical Toxicology ...